Infertility Evaluation - Comprehensive Assessment - Versys Clinics

Infertility Evaluation

Infertility Evaluation Process

The first step in infertility treatment is evaluation, aimed at identifying possible causes and comprehensively understanding the background of infertility. We consider it particularly important that both female and male partners undergo thorough and comprehensive evaluation.

The evaluation follows the Versys Clinics ESHRE ARTCC accredited protocol, which adheres to the highest level of international professional guidelines. Based on the examination results, our specialists prepare a personalized treatment plan for the couple.

ESHRE ARTCC Accredited Protocol (C-0004)

Comprehensive Assessment Approach

All necessary examinations can be performed at the Versys Clinics Human Reproduction Institute and can be completed in a few personal visits without waiting lists. Our evaluation process ensures both partners receive complete assessment using internationally recognized standards.


Female Evaluation

Blood Tests - First Round (Cycle Independent)

Viral Screening

• HIV 1-2 antibodies and HIV-1 antigen
• Hepatitis B virus (HBV): HBsAg, Anti-HBs, Anti-HBc
• Hepatitis C virus (HCV) – anti-HCV
• Cytomegalovirus (CMV) – IgG, IgM
• Rubella – IgG, IgM
• Herpes simplex virus (HSV) 1-2 – IgG, IgM
• Treponema pallidum (IgG/IgM and PRP)
• Toxoplasma antibodies

Genetic & Metabolic Tests

• Karyotype (genetic chromosome analysis)
• Anti-Müllerian hormone (AMH)
• Fasting insulin resistance test
• Complete blood count, ESR, electrolytes
• Liver/kidney profile, lipids, coagulation panel
• Blood group + antibody screening
• Vitamin D level determination

Specialized Screening Tests

Thrombophilia Screening

• Factor V, Factor II, MTHFR

Immunological Antibody Screening

• ANA, ENA, ds-DNA
• Cardiolipin G/A/M
• B2-GPI IgG/IgA/IgM
• Annexin V IgG, Annexin V IgM
• Anti-prothrombin antibodies
• Anti-TPO, anti-TG
• TTG IgA, TTG IgG

Blood Tests - Second Round

Basic Hormones (Cycle Days 2-5)

• FSH, LH, TSH, PRL
• E2, P4, Testosterone
• DHEA-S

Advanced Reproductive Tests

  • ERMap/ERA: Endometrial receptivity analysis
  • EMMA + ALICE: Endometrial microbiome analysis
  • ImMap: Endometrial immunological evaluation
  • Carrier Screening: Genetic mutation screening
  • WOMAM Test: Miscarriage and thrombosis risk assessment
  • KIR/HLA-C: Maternal immunological rejection screening

Gynecological Examinations

  • Transvaginal ultrasound
  • Cytology
  • Vaginal swab culture
  • Diagnostic hysteroscopy
  • Surgical hysteroscopy (if needed)

STD 7 Panel

  • Gardnerella
  • Trichomonas
  • Gonorrhea
  • Chlamydia
  • Mycoplasma
  • Ureaplasma
  • Herpes

Male Evaluation

Blood Tests

Viral Screening

• HIV 1-2 antibodies and HIV-1 antigen
• Hepatitis B virus (HBV): HBsAg, Anti-HBs, Anti-HBc
• Hepatitis C virus (HCV) – anti-HCV
• Treponema pallidum (IgG/IgM and PRP)

Genetic & Hormonal Tests

• Karyotype
• Thrombophilia screening: Factor V, Factor II, MTHFR
• Hormone profile: FSH, LH, TSH, prolactin
• Estradiol, testosterone, free testosterone
• Vitamin D level

Andrological Examinations

  • Sperm Analysis (Spermiogram)
  • Sperm Culture
  • Sperm DNA Fragmentation (Flow cytometry)
  • Acrosome Reaction Test
  • ROS Testing (Flow cytometry)

Male STD 6 Panel

  • Gardnerella
  • Trichomonas
  • Gonorrhea
  • Chlamydia
  • Mycoplasma
  • Ureaplasma

Advanced Sperm Testing

  • DNA fragmentation analysis using flow cytometry
  • Reactive oxygen species (ROS) measurement
  • Acrosome reaction functional testing
  • Comprehensive sperm quality assessment
  • Fertility potential evaluation
  • Treatment planning based on results

Comprehensive Evaluation for Optimal Treatment Planning

Our thorough evaluation process ensures that both partners receive complete assessment using ESHRE ARTCC accredited protocols, enabling our specialists to create the most effective personalized treatment plan for your fertility journey.

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